The Russian-American duo lost to the Swiss Belinda Bencic and Gilles Teichmann with a score of 3:6, 3:6.
The duration of the match was 1 hour 17 minutes.
The prize fund of the tournament is more than $8 million. The competitions are held from March 6 to 19.
Earlier, Shamil Tarpishchev admitted that Daniil Medvedev could have been given inaccurate information about coverage in Indian Wells.