The game at the Bay Arena stadium in Leverkusen ended with a score of 2:2.
As part of the German club, goals were scored by Moussa Diaby (48th minute), Florian Wirtz (59th), Axel Disasi (92 + 2).
The Monegasques scored Krepin Dyatta (74th).
Lukasz Hradecky scored an own goal (ninth).
The Russian midfielder of "Monaco" Alexander Golovin spent 71 minutes on the field, but was not marked by productive actions.
The return match will take place on 23 February.
Earlier it was reported that Rafinha's goal saved Barcelona from defeat in the match against Manchester United.