Vegas has a 2-0 advantage in the final series, which is decided in a best-of-seven. The next game will be played in Florida on the night of Friday.
"It feels good. You want to win every game, so nice feeling," Karlsson told SVT Sport. "I think we were there from the start, we did a great first period. We play good hockey and that's why we win," said Karlsson after the 7-2 win.